DOP087 Microbial colonization at weaning period determines colitis severity in adult mice

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

RORα-Mediated Purkinje Cell Development Determines Disease Severity in Adult SCA1 Mice

Spinocerebellar ataxia type 1 (SCA1) is one of nine inherited, typically adult onset, polyglutamine neurodegenerative diseases. To examine whether development impacts SCA1, we used a conditional transgenic mouse model of SCA1 to delay the postnatal expression of mutant ATXN1 until after completion of cerebellar development. Delayed postnatal expression of mutant ATXN1 led to a substantial reduc...

متن کامل

The meaning of weaning: influence of the weaning period on behavioral development in mice.

Maternal care during the first week postpartum has long-term consequences for offspring development in rodents. However, mother-infant interactions continue well beyond this period, with several physiological and behavioral changes occurring between days 18 and 28 PN. In the present study, we investigate the long-term effects on offspring behavior of being weaned at day 21 PN versus day 28 PN. ...

متن کامل

Microbial colonization of the intestinal epithelium in suckling mice.

Colonization by indigenous microorganisms of the mucosal epithelia of the large bowels of suckling mice was followed by microbial culture techniques and by light, fluorescence, and electron microscopy. Certain microbes colonize in distinctive patterns the cecal and colonic epithelia in these mice. Coliforms and enterococci colonize the large bowel 7 to 9 days after birth and reach high populati...

متن کامل

Microbial colonization of endotracheal tube in intensive care unit patients

Microbial biofilms has remained a major complication of tracheal intubation in patients requiring ventilator equipment. The aim of this study was to characterize bacterial and fungal biofilms in endotracheal tubes from intensive care unit (ICU) patients in Ahwaz, Iran. In this cross-sectional descriptive study, patients admitted to ICU that required mechanical ventilation for at least 24 hours ...

متن کامل

Metabolome progression during early gut microbial colonization of gnotobiotic mice

The microbiome has been implicated directly in host health, especially host metabolic processes and development of immune responses. These are particularly important in infants where the gut first begins being colonized, and such processes may be modeled in mice. In this investigation we follow longitudinally the urine metabolome of ex-germ-free mice, which are colonized with two bacterial spec...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Crohn's and Colitis

سال: 2017

ISSN: 1873-9946,1876-4479

DOI: 10.1093/ecco-jcc/jjx002.124